نتایج جستجو برای: antihistaminic effect
تعداد نتایج: 1641896 فیلتر نتایج به سال:
the β2-adrenergic effects of macerated extract, aqueous extract, ethanol extract, and essential oil of carum copticum, 5 nm propranolol, and saline were tested by performing cumulative log concentration-response curves of isoprenaline-induced relaxation of precontracted isolated guinea pig tracheal chains in three different conditions including: non-incubated (group 1, n=9) incubated with 1 µm ...
in a previous study, the relaxant and anticholinergic (functional antagonism) effects of bunium persicum (b. persicum ) have been demonstrated on guinea pig tracheal chains. to elucidate the other mechanisms responsible for this relaxant effect, the inhibitory effect of this plant on histamine h1 receptors was examined in this study. the antihistaminic effects of aqueous and macerated extracts,...
Bauhinia racemosa Lam. (Caesalpiniaceae) leaves have been used in the treatment of asthma traditionally and we therefore undertook this study to scientifically validate its benefit in asthma using suitable animal models. Antihistaminic principles are known to be useful in the treatment of asthma; hence, in the present work, the antihistaminic activity of an ethanol extract of B. racemosa (at a ...
Similar compounds not containing this molecular configuration are devoid of histamine activity. For obvious reasons it is not only impossible but impractical to check histamine formation. Almost a quarter century ago attempts were initiated to make available an antagonist which would either successfully combat formation of histamine or nullify its effects. This presented many difficulties. Natu...
A series of [1, 2, 4]triazolo[1, 5-b]pyridazines (5) and imidazo[1, 2-b]pyridazines (6) having cyclic amines was synthesized and evaluated for antihistaminic activity and inhibitory effect on eosinophil infiltration. When a piperidine or a piperazine containing a benzhydryl group and a suitable spacer was incorporated at the 6-position, the fused pyridazines were found to exhibit both antihista...
Kurtin, Bierman and Yontef (1) reported on the prevention of ultraviolet erythema by iontophoresis of a solution of Pyribenzamine (N -pyridyl-N -benzyl-N -dimethylethylene diamine hydrochloride) into the skin prior to exposure to a hot quartz ultraviolet lamp. They attributed this effect to the "antihistaminic "action of Pyribenzamine in the tissues. We were able to confirm the findings of Kurt...
In connection with several recent publications"' on reaction in children after injection of H. pertussis vaccine, it might be of interest to report our own observations on the action of antihistaminic drugs on mice sensitized by this vaccine. In a previous publication8 it was reported that treatment of mice with H. pertussis vaccine renders these animals highly sensitive to histamine. These fin...
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